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Appendix Appendix Equations Used for Obtaining CVD 10-Year Risk, Based on the Cox Model (based on DAgostino RB et al

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The subjects treated with semaglutide lost 9.1% of their body weight on average over 12 months, equating to 19.2lb (8.7kg)

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The peptide reconstitution calculator determines how much water to add for desired concentrations

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3.5 Metagenomic analysis demonstrates that SE reshapes the gut microbiome and its metabolic function To investigate the origin of the altered bile acid profiles, we performed shotgun metagenomic sequencing of fecal samples

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