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Platelet-activating factor (PAF) is an important lipid mediator involved in inflammation

Immunoblot analysis of ferroptosis-related proteins after transfection with Flag-Mock or Flag-SIRT1 into control and SYNCRIP-deficient U373, U87, and HS683 cells

Common AEs included fatigue (46%), diarrhea (24%), cardiotoxicity, ophthalmic toxicity, neurotoxicity, renal toxicity, and metabolic dysregulation 163

However, no differences were observed in isometric torque production, specific torque, or histological measures of myofiber cross-sectional area or collagen deposition across any treatment group