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In contrast to the enhancement of spontaneous excitatory postsynaptic transmission (Mietlicki-Baase et al., 2013), using retrograde labeling of VTA to nucleus accumbens (NAc) medial shell projecting neurons, in vitro patch-clamp recordings showed that exendin-4 selectively inhibits the miniature excitatory postsynaptic currents (mEPSCs) within the dopaminergic VTA-to-NAc projection neurons (Wang et al., 2015

Glutathione is an abundant intracellular thiol (a compound containing a sulfhydryl group) and low molecular weight tripeptide found in living cells.* Serving as an antioxidant in all types of tissues, the antioxidant functions of glutathione include recycling vitamins C and E to their antioxidant form to minimize oxidative stress.*

As we age, our body's natural production of glutathione decreases, which can lead to increased oxidative stress and cellular damage

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