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In exploring the treatment of obesity and its associated complications, such as Type 2 diabetes and cardiovascular disease, a prominent and popular target is the Glucagon-Like Peptide-1 Receptor (GLP-1R)

Near-term cost driver: Prescription drug trend can rise several percentage points for plans that cover GLP-1s

It's important to note that these medications carry a boxed warning for risk of thyroid C-cell tumors and are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)